Antimicrobial and Antioxidant potential of Achyranthes aspera Linn. and Its increased prevalence in Cosmetics
*Manoj Kumar Singh1 , Anil Kumar Singh2 and Md. Sarfaraz Ahmad3
1Department of Botany, KR College, Gopalganj, Bihar (India) 2Associate Professor, Department of Botany, B R A Bihar University, Muzaffarpur, Bihar (India) 3Associate Professor, Department of Botany, Gopeshwar College, Hathwa, Gopalganj, Bihar (India) (Jai Prakash Vishvidyalay, Chapra, Bihar, India) Email: manojkumarsingh12672@gmail.com
ABSTRACT
Achyranthes aspera Linn. (family: Amaranthaceae) is an indigenous medicinal plant found in Asia, South America, and Africa. It is known to contain active components like tannins, phenol, alkaloids, flavonoids, terpenoids, saponins etc. The study emphasize on the comparison of antioxidant and antibacterial activity among root, stem and leaf extract of A. aspera. The evaluation of scavenging activity was screened based on three methods of antioxidant activity, DPPH Assay, FRAP Assay and ABTS Method. A.aspera root extract showed higher percentage scavenging activity (66.32%) at 500 (μg/ml). IC50 for for root, leaf and stem extract was found to be 299.4 (μg/ml), 379.75 (μg/ml) and 467.31 (μg/ml). The scavenging activity estimated in the extracts of A.aspera using Ferric reducing-antioxidant power (FRAP) assay showed best results in case of stem extract (184.15%) at 500 (μg/ml). FRAP assay showed comparable percentage inhibition in the root (86.81%), leaf (85.23%) and stem (85.71%) extracts. Out of the three extracts root (R.E), stem (S.E) and leaves (L.E), root extract was observed to possess potent activities with maximum antibacterial activity at highest concentration (187.5mg/ml). FTIR spectra was used to analyze functional groups.