Effect of antibiotics on L-glutamic acid production by Corynebacterium glutamicum X680
1Subhadeep Ganguly and *2Smaranika Pattnaik
1Department of Physiology, Vidyasagar College, 39-Sankar Ghosh Lane, Kolkata-700006, (India) 2Department of Biotechnology and Bioinformatics, Medical Biotechnology Laboratory, Sambalpur University, Jyoti Vihar, Burla-768019 (India) *Address for correspondence: smaranika2010@gmail.com
ABSTRACT
L-glutamic acid is a proteinigenic, non-essential amino acid with immense industrial value1. Its fermentation in industrial scale was started in 19577. Addition of antibiotics was found to be effective for its production improvement. In my previous investigation, I showed stimulatory effect of penicillin G on extracellular accumulation of L-glutamic acid by the mutant5. In connection of this study, the investigation was undertaken to examine the effect of some other antibiotics on extracellular accumulation of L-glutamic acid by the biotin auxotroph Corynebacterium glutamicum X680.