In vitro Anti-inflammatory and Antioxidant Potential of Calotropis procera (Aiton) Dryand Flowers
*Vaijanath V. Kharat1, Saheb L. Shinde2 and Kailash S. Sontakke3
1Department of Botany, Yeshwant Mahavidyalaya, Nanded Dist. Nanded-431602 (India) E-mail - kharatv1986@gmail.com, 2Department of Botany, Rajiv Gandhi College, Mudkhed Dist. Nanded-431806 (India) E-mail- sahebshinde4@gmail.com, 3Department of Botany, Gopikabai Sitaram Gawande Mahavidyalaya, Umarkhed, Dist. Yavatmal-445206 (India) E-mail – sontakke@gsgcollege.edu.in *Corresponding author: kharatv1986@gmail.com
ABSTRACT
The plant Calotropis procera (Aiton) Dryand belongs to plant family Asclepiadaceae is a deciduous wild shrub. The present study aimed to evaluate the in vitro antioxidant and anti-inflammatory activities of metabolic extract of flowers Calotropis procera (Aiton) Dryand. The previous result indicates the presence of a varied group of phytochemicals such as alkaloids, Anthraquinones, Carbohydrates, Flavonoids, Glycosides, Phenols, Terpenes, Saponins. Calotropis procera in water extract showed the percentage of DPPH radical scavenging activity (73.29±2.020) as compared to standard Ascorbic acid (93.94 ±0.63). The Photometric in vitro antioxidant activity of Calotropis procera flower extracts in non-polar solvent (Hexane) was shown highest OH radical scavenging activity (62.22 ±2.020) as compared with standard ascorbic acid (57.77±0.73). The photometric in vitro antiinflammation activity by protein denaturation of Calotropis procera flower extracts in Water solvent was shown to have the highest activity (87.17±1.020) as compared to standard Diclofenac sodium (92.30 ± 0.47).