Daniel Tarmast1, Vahid Imanipour1, Mehdi Kasbparast JR2, Ali Sajedi1, and Korosh Morovatnya1

1Department of Physical Education and Sport Sciences, Parand Branch, Islamic Azad University, Parand City, Tehran, Iran 2Department of Sport Injury and Biomechanics, Faculty of Physical Education and Sport Sciences, Islamic Azad University, Karaj Branch, Alborz, Iran


Different typesof exercise seem to have medical benefits for many diseases such as asthma.The objective of this research was to study the effects of two types of exercise:1) a single bout, and 2) a threemonthexercise on serum cytokine – interleukin-1(IL-1) concentrations in 32adult asthma patients (age 36±5.5 y, weight 94.3±9.0 kg, height 173±6.0 cm). The patients of the study randomly divided to training and control groups. For this purpose, the participants of the training group performed a single bout of exercise on an ergometer. Before and after the exercise, blood samples were taken for serum determinations of IL-1. Also, a spirometry test was done to diagnose lung conditions of the patients. After one week, the participants started the endurance exercise, and they exercised 3 times per week for threemonths.A blood sample was also taken after one month of the last trial. Participants’anthropometrical indexes were examined during two occasions. All data were compared by t - tests.Resultsindicated that after a single bout of exercise IL-1 significantly increased compared to the baseline (p<0.05), and subsequent to the three-month exercise IL-1 significantly decreased (p<0.05). But, after one month of detraining, the IL-1declined to the baseline. No differences were found in the IL-1 of the control group. We conclude that endurance exercise can help asthma patients by the anti-inflammatory effect.

Key words : Endurance exercise, Interleukin-1, antiinflammatory, asthma patients.

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