Sheik Aliya1, Abdul Rasheed Md2 and Yalavarthy Prameela Devi2

1Department of Biotechnology, Jawaharlal Nehru Technological University, Hyderabad-500085 (India) 2Department of Zoology, Kakatiya University, Warangal-506009 (India) *Email:


The present study was conducted to evaluate the antibacterial activity of unripe Carica papaya fruits. Agar well diffusion method was employed to test antibacterial activity of C. papaya unripe fruit’s methanolic extract on human pathogens which causes nosocomial infections. The methanolic extract exhibited significant dose dependent antibacterial activity comparable to conventional antibiotic (Streptomycin) used against clinically isolated pathogens. These results suggest that the methanolic fraction of unripe C. papaya fruit, as a potential source of natural antibacterial constitute. Further investigations are being carried out in our laboratory to identify the active bio-ingredient(s) of extract and establish the exact mechanism of action in order to explain their therapeutic efficacy.

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