Biosynthesis of Silver nanoparticle from cultivated Mushroom (Calocybe indica P&C) and its Antibacterial activity
1*S P Suvetha and 2R Siva
1Research Scholar, 2Assistant Professor, Department of Plant Biology and Plant Biotechnology, Shrimathi Devkunvar Nanalal Bhatt Vaishnav College for Woman, Chennai-600044 (India) *Email:suvethaperumalsdnb@gmail.com
ABSTRACT
Environmental friendly green synthesis of silver nanoparticles from cultivated mushroom utilizing different spawn grains reduced by different substrates has shown essential benefits due to the fact that of potential therapeutic applications. The found AgNPs were categorized by UV - visible spectrum, FTIR and SEM which showed the reduction of Ag+ ions to Ag0. Further, the aqueous extract was analyzed for qualitative and quantitative phytochemical screening and statistical analysis (one- way ANOVA) were reported to check the significance over substrate and their harvest. The synthesized AgNPs shows more absorption UV spectrum (420nm) and FTIR vibrational peaks (3278, 2933, 1634, 1372, 1018.88 and 933cm-1) respectively. SEM analysis was also performed. Antibacterial efficacy was studied against Escherichia coli, Staphylococcus aureus, Bacillus subtilis and Pseudomonas aeroginosa by disc diffusion method. The present study revealed that the synthesized AgNPs from Calocybe indica play a major role in developing the therapeutic drug against bacterial infectious disease and other health associated disorders.