Bio-fabrication of silver nanoparticles from Garlic clove extract as a novel antibacterial agent
Ashajyothi C*
Department of Biotechnology, Vijayanagara Sri Krishnadevaraya University, Ballari-583 105 (India) *Corresponding author: Dr Ashajyothi C E-mail: drashajyothic@vskub.ac.in, ORCID id: 0000-0002-6927-681X Mobile: 8073259740
ABSTRACT
Recent research on the biosynthesis of nanoparticles is based on the use of biopaths with low-cost and safe production strategies, biocompatible materials to manufacture the structures, and nano-based formulations for specific applications. Current work is aimed at assessing the biological activity of bio-silver nanoparticles in vitro using clove extracts from Ginger (Allium sativum L). Garlic is a notably studied herb and contains key bioactive compounds. Organosulfur or thiol-based organic compounds are the main bioactive compounds present in garlic. In many research these organic compounds proved for having numerous biological and therapeutic activities and hence marked for formulation and synthesis of various biogenic nanocomponents. Using garlic extract, silver nanoparticles are produced by an environmentally friendly method and their antibacterial activity was evaluated. Size and the structural confirmation of nanoparticles was done by using UV-Visible, Electron Microscopy, X-ray Diffraction and Fourier-infrared spectroscopic studies. Polydisperse type of distribution of silver nanoparticles was confirmed by Transmission electron microscopy study.