Varsha M. Chaudhari

Department of Microbiology, P.S.G.V.P. Mandal's S. I. P. Arts, G.B. Patel Science and STKVS Commerce College, Shahada, Dist-Nandurbar - 425 409 (India) Email: varsharaj2913@gmail.com

ABSTRACT

The present work was conducted to determine the antimicrobial activity of stem and leaf extract of some indigenous medicinal plants against some human pathogenic strains like Staphylococcus aureus, Bacillus, Escherichia coli, and Pseudomonas. Leaf and stem parts of the medicinal plant Gulvel (Tinospora cordifolia L.) was extracted in different solvents like Ethanol, Methanol, Dimethyl sulfoxide and Distilled water. In vitro antibacterial activity was performed by the agar disc diffusion method. The results obtained revealed that most susceptible Gram-positive bacteria was found to be Staphylococcus aureus, while the most sensitive Gram-negative bacteria was Escherichia coli as well as Pseudomonas spp. for stem extract of Gulvel.

Key words : Tinospora cordifolia L., Antimicrobial activity, Medicinal plants, Agar disc diffusion method

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