Pharmacological evaluation of Polygonatum verticillatum (L.) All. of Indian Ayurvedic medicinal plant
1Sahil Saini; 1Harish Kumar; 2Sonali Bihana; 3,#Anil Kumar Sharma; 4Seema Ramniwas and 3Ajay Kumar Gupta*
1M.M. College of Pharmacy, 3Department of Biotechnology, 2Gaur Brahman Ayurvedic College, Rohtak-124001 (India) Maharishi Markandeshwar (Deemed To be University), Mullana, Ambala-133203 (India) 4University Centre for Research and Development, University Institute of Biotechnology Chandigarh University, Gharuan, Mohali-140413 (India) * Corresponding Author: akgupta.in@gmail.com or # anibiotech18@gmail.com
ABSTRACT
Polygonatum verticillatum (L.) All is a useful medicinal plant found in the himalayan region at elevations ranging from 2400 to 2800 metres. The species’ rhizome is used in the preparation of Chyavanprash and many other ayurvedic formulations. Saponins, phytohormones, flavonoids, alkaloids, flavonoids, serine, diosgenin, lysine, santonin, lysine, sitosterol, calarene, aspartic acid, piperitone, docasane, calarene, and other active constituents have been discovered in this species. It also has antimalarial, urease inhibitor, anti-inflammatory, lipoxygenase inhibitor, antipyretic, anticonvulsant, tracheorelaxant, anticonvulsant, diuretic, tracheorelaxant, antinociceptive, antidiarrheal, antifungal, and insecticidal properties. Because of its broad therapeutic effects, especially those of its rhizome, the plant has gained attention in traditional medicinal systems. Because of the huge and uncontrollable collection of wild material, it now falls into the category of threatened plants. So various efforts are made to conserve this plant such as ex situ and in situ conservation. This paper provides a brief overview of this plant’s botanical, traditional, bioactive components, pharmacological, and conservation-related aspects.