1*S.P. Suvetha and 2Dr. R. Siva

Department of Plant Biology and Plant Biotechnology Shrimathi Devkunvar Nanalal Bhatt Vaishnav College for Women, Chromepet,Chennai-600044 (India) 1*corresponding author -suvethaperumalsdnb@gmail.com


Myconanotechnology has gained a great attention now a days due to increased Bio-medical application , eco- friendly nature, cost – efficient without side effects. The present study was focused on mycosynthesis of Zinc Oxide nanoparticle using the mycelium of Macrocybe crassa with zinc nitrate as precursor. The synthesized nanoparticle was further characterized by UV-VIS spectroscopy, FTIR spectroscopy and SEM anlaysis which proved the presence of spherical shaped nano structure. The Anti-bacterial activity of synthesized nanoparticle was studied using four bacteria, a high zone of inhibition was obtained in Pseudomonas florescens followed by B. subtilis, S. aureus, E. coli. The Anti-tumor effect of ZnO nano particle was also analysed against DLA cell line using tryphan blue exclusion method. The synthesized ZnO nanoparticle could be a excellent supplement when used along with anti-cancer drug in the medicinal field after proper in vivo analysis.

Key words : Mycosynthesis, Macrocybe crassa, DLA cell line, Anti-tumor, SEM.

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