GC-MS analysis, phytochemical screening and Antimicrobial potential of methanolic extract of Malva parviflora L. and Phyllanthus niruri, L.
*Vijay Pal, 1Sheetal Tanwar, 2Aarti Chaudhary, and 3Rahul
#Department of Botany, Shri ShRaddhanath P.G. College Todi, Gudha Gorji, Jhun Jhunu-333022 (India) 1Department of Botany, GGDSD College, Palwal-121 102 (India) 2Department of Botany, Raja Balwant Singh College, Dr. Bhimrao Ambedkar University, Agra-282 002 (India) 3Department of Botany, Maharshi Dayanand University Rohtak-124001 (India) #(e-mail: Gujjarvijay66@gmail.com; Mobile: 9466931266)
ABSTRACT
This investigation aimed to examine the antibacterial activity and phytochemical analysis of Malva parviflora L. and Phyllanthus niruri L. whole plant. The methanolic extract was analyzed by using GC-MS, and the results showed that it contained a variety of phytochemicals like Borane, chlorodipropyl; Propane, 1,2,3 trichloro; 2-Troponyl difluoroborate; 1,4 Benzenedicarboxylic acid; dimethyl ester; Methyl 12,13 tetradecadienoate; 7-Hexadecenoic acid; methyl ester; Methyl 9,10 octadecadienoate; beta-Sitosterol acetate; 1-(10,10- Dimethyl-3,3- dioxo-3-thia-4- azatricyclo[5.2.1.0(1,5)] dec-4-yl)-3- methylpent4-en-1-one; Methyl 8,9- octadecadienoate in Malva parviflora whole plant. Phyllanthus niruri also shows the phytochemicals like Cyclopentyl-methylphosphinic acid; 2- isopropyl- 5-methylcyclohexyl ester; Methyl 9,10- octadecadienoate; 2,3-Bis [(4- hydroxy-3- methoxyphenyl) methyl] butane-1,4-diol, tetramethyl ether; Methyl 11,12- tetradecadienoate; Methyl 12,13- tetradecadienoate. Research has also been done to investigate the antibacterial activity of the methanolic extract against a variety of bacterial and fungal species, when employed in concentrations of 1μL, the methanolic extract of Malva parviflora showed a minimum inhibition zone of 8 mm against the bacteria, Escherichia coli and 5 mm Serratia marcenscens. Similarly utilized in concentrations of 1 μL for antifungal action 7 mm of minimum inhibition zone against Aspergillus niger and 5mm against Penicillium digitatum. Similarly, Phyllanthus niruri shows 5mm of inhibition against Escherichia coli and Serratia marcenscens. The 5mm of inhibition was observed against Aspergillus niger and 10 mm against Penicellium digitatum. These findings imply that Malva parviflora and Phyllanthus niruri have the potential to be used in pharmaceutical industries, both may work as promising natural antibacterial agents