Effects of L-T3 on the plasma glucose, protein and amino acid levels of the tree sparrow, Passer montanus malaccencis
1*Mayanglambam Bimolata Devi, 2Kshetrimayum Pratima Devi, 3Laishram Sanahanbi Devi and 4Asem Ibemhal Devi
*1Department of Zoology, Kakching Khunou College, Kakching District, Manipur-795103 (India) 2Department of Zoology, Modern College, Imphal East, Manipur-795005 (India) 3Department of Zoology, Lilong Haoreibi College, Thoubal District - 795130 (India) 4Department of Botany, Shree Shree Gourgobind Girls’ College, Imphal East-795010 (India) Corresponding Author: *mbimolata00@gmail.com
ABSTRACT
The two major thyroid hormones are L-thyroxine (L-T4) and Tri-iodothyronine (L-T3) which they take an important role in the oxidative and metabolic process of the body of homoiothermous animals. In birds,L-T4 and L-T3 are important in the regulation of the body metabolism performing a number of diverse functions. The dose dependent effects of L-T3 on the levels of glucose, proteins and amino acids of plasma were studied on the tree sparrow, Passer montanus malaccencis. Administration of different doses of T3 to normal intact birds produced a significant dose dependent elevation in plasma glucose level as compared to their respective controls. The low dose of T3 decreased the plasma amino acid level from 16.43±3.77 to 12.04±0.97 mg/ml but at mid and high doses of L-T3, the plasma amino acids of the bird increased from 87.33±2.60 mg/ml for control to 105±3.46 mg/ml for high dose and 102±4 mg/ml for mid dose. The plasma protein level was considerably increased at the low dose of T3, 20.99±2.6 mg/ml for control to 29.20±1.7 mg/ml. On the contrary, the mid and high doses of T3 caused decreased of plasma protein levels from 24.14±1.5 mg/ml for control to 19.45±1.13 mg/ml for mid dose and 19.22±0.6 mg/ml for high dose. Plasma glucose levels at mid dose was found to be 1.13±0.06 mg/ml and at high (5 μg) dose was .21±0.1 mg/ml and for the control was 0.921±0.05 mg/ml. The results suggested that administration of both mid and high doses of LT3 to normal intact birds caused hyperglycemia as showed by the increased in plasma glucose levels. The energy demand imposed upon by the prolong administration of high dose of L-T3 caused the utilization