A review on association of Gut microbiome with irritable Bowel syndrome
*Sushma Patkar, Abhiseka Dash, B. Kalpana and Khushboo Choudhary
Department of Genetics and Biotechnology Bhavans Vivekananda College of Science, Humanities & Commerce Sainikpuri, Secunderabad, 500094 India Corresponding author sushma.biotech@bhavansvc.ac.in abhishekadash185@gmail.com Kalpana_bellary@yahoo.com khusbuchoudhary777@gmail.com
ABSTRACT
Abstract The human microbiome is associated with several diseases. The most prominent being gastrointestinal diseases and host microbiome interactions. However the microbial mechanisms in GI disorders are not completely established. Irritable Bowel Syndrome IBS remains one of the prominent gastrointestinal disorders with significant changes in gut microbiome composition. IBS has a very severe impact on socio economic and patient’s lifestyle. This review provides information about the emerging role of gut microbiome in the pathogenesis of IBS.