Phytochemical , Antioxidant and Antidiabetic Activities of Pistia stratiotes L. Assam, India
Pritimani Bharali1, Rantumoni Sharma1, Madhushmita Nath1, Diptimoni Devi1 and Namita Nath1*
1Department of Botany, Gauhati University, Guwahati - 781014 (India) *Corresponding author: email: nathnamita1@gauhati.ac.in
ABSTRACT
Diabetes Mellitus is a very common metabolic disorder. The digestive enzymes α-glucosidase and α-amylase are pivotal in breaking down starch into glucose. Consequently, inhibiting the activityof these enzymes is recognized as significant approach in the management of diabetes. Pistia stratiotes L. arecommonlyused in traditional remedies due to their various health benefits. The main objective of this study was to analyze the total phenolic content, total flavonoids content, antioxidant properties, enzyme inhibitoryactivityagainst α-glucosidase and α-amylase. The Phenol and flavonoid content was found to be highest in P. stratiotes leaf methanolic extract 169.15 mg GAE/100 g extract weight and 224.74 mg QE/100 g extract weight respectively. The methanolic of P. stratiotes leaf showed higher antioxidant potential than the P. stratiotes root methanolic extract according to the DPPH and ABTS+ assay. Furthermore, methanol extract P. stratiotes showed significant inhibitory activityagainst α-amylase and α-glucosidase with IC50 values of IC50 41.72 µg/mLIC50 47.72 respectively. Based on these results, it is understood that methanolic extract is the potential source of an antioxidant as well as antidiabetic activity.