Antibacterial activity of the rhizome oil extract of Curcuma caesia Roxb. against UTI causing bacteria Escherichia coli
1Bhanu Priya Pegu and 2Pradip Kumar Baruah
1,2Department of Botany, University of Science and Technology Meghalaya - 793101 (India) 1Correspondimg author Email id :- bhanupegupriya01@gmail.com 2Email id :- pkbaruah10@yahoo.com
ABSTRACT
Plants have medicinal values and serve as potential source of medicine. Curcuma caesia Roxb. belonging to the familyZingiberaceae is a less known valuable medicinal plant . In this study the antibacterial activity of rhizome oil extract of Curcuma caesia Roxb. was evaluated against UTI causing bacteria Escherichia coli. Phytochemical analysis was carried out using GC-MS method. The oil was extracted by hydrodistillation method and antibacterial activity was analysed by Disc diffusion method. Four commercial antibiotics were choosen and compared with Paper disc(whatman no1 filter paper 5mm) impreganated with oil extract. The oil extract showed a zone ofinhibition of 12-13 mm, which is found to be more susceptible than Penicillin-G and Polymyxin-B. The phytochemical analysis by GC-MS showed 34 peaks out of which 8 peaks were studied. The major compound was found to be Benzofuran, 6-ethenyl-4,5,6,7-tetrahydro-3,6-dimethyl-5-isopropenyl-trans (10.38%). The present study revealed that the oil extract of the rhizome posses antibacterial activity and can be used against UTIs causing bacteria. This antibacterial activity could be possiblely due to the presence of the various compounds.