1Mrunali Jagdish Mhaskey and 2Vaishali Uday Thool

1Research Scholar, Institute for Higher Learning, Research and Specialized Studies, Sardar Patel Mahavidyalaya, Chandrapur - 442402 M.S. India 2Professor, Department of Microbiology, Sardar Patel Mahavidyalaya, Chandrapur - 442402 M.S. India Corresponding Author- Mrunali Jagdish Mhaskey Email- mrunali.mhaskey1996@gmail.com

ABSTRACT

Antibiotic resistance and cancer are two of the major public healthcare challenges the world is facing today. As the number of deaths caused by these diseases continues to rise, there is a growing need for new, naturallyderived drugs that can target these problems effectively. This study explores the potential use of theAyurvedic compound bhasma as an antibacterial and anticancer agent. The bhasma samples were characterized using various techniques, including FTIR, SEM, and EDAX. Abhrak and Tamra bhasma was tested against five isolates each of E. faecalis, K. pneumoniae, and P. aeruginosa for antibacterial activity at three different concentrations (2.5mg, 5mg, 10mg), as well as against MCF7/Breast cancer cell lines for anticancer activity. The results suggest that Tamra bhasma is effective in inhibiting the growth of all isolates of E. faecalis, while Abhrak bhasma is effective against K. pneumoniae and P. aeruginosa isolates. Tamra bhasma also shows greater potential in controlling the growth ofcancerous cells compared toAbhrak bhasma. The study concludes that bhasma has the potential to be a promising therapeutic agent for treating cancer and bacterial infections and could revolutionize modern healthcare.

Key words : Bhasma,Antibacterial,Anticancer, FTIR, SEM with EDAX.

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