Case report on Celphos (Aluminium phosphide) poisoning
Modepalli Poojitha,1 Yekollu Niharika,1 Gutti Keerthi,1 C. Lalitha,2 and K. Arun Chand Roby1
1ACSR Govt. Hospitals, Nellore - 524003 [India] 2Department of Pharmacy Practice, Ratnam Institute of Pharmacy, Nellore - 524346 [India] 3Department of Pharmacy practice Vignan Pharmacy College, Guntur - 522213 [India] CorrespondingAuthor: arunchandroby@gmail.com 1VI th year Pharm D student, 2Assistant professor, 3Associate Professor,
ABSTRACT
Aluminum phosphide is a poison and it occurs due to excess exposure of Aluminium phosphide, which is generally used as a pesticide to kill rodents and insects. It contains Phosphine gas which is mitochondrial poisoning. This is highly toxic. The Centers for disease control, prevention and management have classed phosphine as physically harmful to living, sometimes when 50 ppm.Alumina phosphide needs to react as well as the hydrate but rather acid derivatives between discharge porphyrin. AlP + 3 H2O Al[OH]3 + PH3 AlP + 3 H+ Al3+ + PH3 It is sold under Pest phos, Celphos, Quickphos, Fostox, Salphose and Weevil-cide. When humans consume it, it shows fatal effects. Toxic features like circulatory collapse, metabolic acidosis and renal failure occur within a few minutes of ingestion. It has a high mortality rate of 90-100% of deaths with consumption of 1-3 tablets. There is no specific antidote for this poisoning. It is reported as a leading cause of suicidal deaths in most of India’s northern and southern states. This case involved a patient with Celphos poisoning who ingested two Aluminium phosphide tablets. This case report underscores the importance of Educating illiterates regarding these pesticides and the fatal effect that may be observed. By giving immediate therapy and supportive care patient’s life is saved.