Screening and In-silico approach to evaluate the Diabetic wound healing of phytocompounds against the target protein and Antibacterial activity
*Pragathesh Singh1 , and *Vanitha Nagaraj2
PG And Research Department of Microbiology, Hindusthan College of Arts & Science. Coimbatore - 641028 *Corresponding authors: vanithanagaraj@hicas.ac.in; pragatheshsinghk@gmail.com
ABSTRACT
Diabetic foot infections can be caused by the ubiquitous gramnegative bacterium Pseudomonas aeruginosa. 16.7% of people with diabetes have diabetic foot infections. A gram-negative bacterium called Klebsiella oxytoca was found in a diabetic foot infection. It has a decreased susceptibility to chlorhexidine and is a common and dangerous consequence in diabetes individuals. Gram-positive Staphylococcus aureus and gram-negative Enterococcus sp. bacteria are frequently found in diabetic foot ulcer patients. Escherichia coli is one of these bacteria. Anti-bacterial resistance bacteria are a global concern when it comes to the use of different plant-based herbal medication formulations. This study is to found the phytocompound of herbal plant through insilico molecular docking and in-vitro antibacterial analysis.