Anti-oxidant and Anti-glycation potential of extracts from leaves of Chonemorpha fragrans G. Don. and Ellertonia rheedii Wight
1B. A. Mauna and 1,2T. Parameshwar Naik*
1Department of Botany and Seed Technology, Sahyadri Science College, Shivamogga - 577203 (India) 2Registrar, Bidar University, Bidar - 585226 (India) *Corresponding Author E-mail: maravanjiparameswara@gmail.com
ABSTRACT
Because of wide variety of phytochemicals, Chonemorpha fragrans and Ellertonia rheedii members of the Apocynaceae family were frequently utilized in Indian traditional medicine. The present study aims at screening of extracts from leaves of Chonemorpha fragrans and Ellertonia rheedii for anti-oxidant and anti-glycation activities. The EtOH extract at 100 µg/ml showed maximum activity of 70.78% and 65.83% respectively for E. rheedii and C. fragrans. The extracts of both the plants exhibited excellent H2O2 scavenging, NO scavenging and Xanthine oxidase inhibition. Further, the extracts from both the selected plants also exhibited excellent anti-glycation activity with IC50 82.34 and 87.66 µg/ml respectively. The results were outstanding, and both plants may be implicated in the treatment of carious diseases