Potential antibacterial activity of isolated Caldine alkaloid from Parthenium hysterophorus L.
Aman Saket1 , Heena Choudhary1 , Shivani Singh1 , T. Srinivasan2 and A. K. Shukla1
1Department of Botany, Indira Gandhi National Tribal University, Amarkantak-484887 (India) 2Department of Botany, Central Tribal University of Andhra Pradesh, Vizianagaram - 535003 (India)
ABSTRACT
Parthenium hysterophorus L. is a multifaceted plant that has a wide range of chemical constituents. Aim of this study was to isolate alkaloid from leaf extract of Parthenium hysterophorus L. Isolation of compounds was done through column chromatography techniques, followed by further characterization using the LC-MS/MS, FTIR. An alkaloid Caldine was found present in the leaf extract of the P. hysterophorus. Antibacterial activity of Caldine was evaluated against bacteria Erwinia carotovora and Ralstonia solanocearum. Growth of both bacteria was inhibited by the Caldine. R. solanocearum was more susceptible to the antibacterial action with 18mm zone of inhibition at 150 µL Caldine concentration.