Influence of biofilm formation on the pathogenicity of Klebsiella pneumoniae
*Dhanya. P and A Manivannan**
Department of Microbiology, Hindustan college of Arts & Science, Hindustan Gardens, Coimbatore - 641028 (India) (dhanyapuliyakode@gmail.com) Corresponding Author: Dr. Manivannan A, manivannan.a@hicas.ac.in Mob: 9894294658
ABSTRACT
Klebsiella pneumoniae, a gram-negative bacterium which was long considered as an opportunistic pathogen has diverged itself to become a serious nosocomial and community transmissible microbe. One reason for this increase in pathogenesis can be attributed to its biofilm formation. Although extensive research has implicated the correlation between the microbe’s capacity to form biofilms and how it influences K. pneumoniae drug resistance to antimicrobial agents, the mechanism and direct effect of the biofilm on multi-drug resistance is yet to be fully elucidated. This review sheds light on the interplay between biofilms and other virulence factors, highlighting the importance of biofilms in pathogenesis.