Efficacy of Punica granatum L. peel extract in the treatment of Oral Lichen planus in comparison with Triamcinolone Acetonide 0.1%
Jyothirmai. K1 , Mahalakshmi V.2 , Sudhakara Reddy R.3 , Ananda Babu B.4 , Veerakumari M.5 and Anusha Avvaru6
1-6Department of Oral Medicine and Radiology Vishnu Dental College Bhimavaram - 534202 (India) Corresponding Author: *5Email ID : Veerakumari.m@vdc.edu.in phone number- 8639744859
ABSTRACT
Oral lichen planus (OLP) is a relatively common chronic inflammatory disease affecting oral mucosa. Punica granatum L. is the herb. It has antioxidant, anti-inflammatory, anticarcinogenic, antiviral, antifungal properties etc. The aim of the present study is to evaluate the efficacy of Punica granatum peel extract in the treatment of oral lichen planus in comparison with triamcinolone acetonide 0.1%. A sample of 40 patients who were clinically and histopathologically diagnosed with OLP were included and randomly assigned into two groups. Test group was given Punica granatum peel extract and control group was given triamcinolone acetonide 0.1%. Subjective symptoms and objective signs were recorded on weekly basis until the remission of symptoms. Results depicted that Punica have shown comparable results with that of topical corticosteroids. So, it can be used as an effective alternative for topical corticosteroids.