*Ashish Gupta

Acropolis Institute of Pharmaceutical Education and Research, Indore - 453771 (India) Correspondence Email ID: ashish.pharma87@gmail.com

ABSTRACT

In the pharmaceutical sector, microemulgel is a novel and promising drug delivery technology. The oil, surfactant, and clear water phase form a stable dispersion that can be either kinetically or thermodynamically stable. Due to its advantages over current oral and topical drug delivery methods, such as its capacity to prevent poor drug bioavailability and phramacokinetic variability, microemulgel has become a popular new transdermal drug delivery approach. Adding micro-emulsion with gel creates a novel approach that enhances stability and enables rapid, controlled drug release. Enhancing medication absorption and lipophilic drug therapeutic profile is the goal of the formulation-related technology known as the Microemulgel drug delivery system. The great patient tolerance of the formulation has led to a notable increase in microemulgel use in recent years. Due to the preparation’s improved patient acceptance—which includes its nongreasy nature, ease of application, simple spreadability, and favorable safety and therapeutic profile—microemulgel’s use has expanded recently. Notwithstanding these obstacles, microemulgel holds great promise for the future as the main topical delivery system for lipophilic medications. This review emphasizes on the various kinds of microemulsions, their benefits over alternative dosage forms, and the ways in which they are made, described, and used in various sectors.

Key words : Microemulsion, Microemulgel, Gelling agent,Topical drug delivery, Lipophilic drug, Phase diagram

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