Phytochemical composition and antioxidant property of Acalypha indica L. fractions
R.G. Dhangar1 , A.V. Baviskar2 , V.P. Nage3 , N.L. Shirole4 , R.D. Wagh4 , S.V. Chawre3 , H.V. Deore1 and R.L. Shirole1*
1Department of Pharmacology DCS’s A.R.A. College of Pharmacy, Dhule - 424002 (India) 2Department of Pharmaceutics, Vishvabharati Academy’s College of Pharmacy, Sarola Baddi, Ahmadnagar - 174103 (India) 3Department of Kayachikitsa, Government Ayurvedic College, Nagpur - 440024 (India) 4Department of Pharmaceutical Chemistry DCS’s A.R.A. College of Pharmacy, Dhule - 424002 (India) *Corresponding author : Dr. Shirole R. L. (M. Pharm., Ph.D.) Associate Professor of Pharmacology, Dept. of Pharmacology, DCS’s A. R. A. College of Pharmacy, Dhule - 424002 (India) Email id: rahulshirole@gmail.com Tel: 02562-2243021
ABSTRACT
Oxidative stress has been demonstrated to significantly contribute to the onset of several disease processes in the human body. Natural antioxidants are efficient in safeguarding the human body against oxidative damage caused by free radicals. Plants are a significant source of numerous pharmaceuticals from various categories that are recognized for alleviating diverse ailments, including oxidative stress. Acalypha indica belongs to the Euphorbiaceae family. Extracts from the leaves of this plant have been documented to exhibit diverse biological activity. The current work involved the fractionation of methanolic leaf extract of Acalypha indica L. into ethyl acetate and n-butanol. The extracted extract and fractions underwent preliminary phytochemical screening and investigation of antioxidant activity. In vitro tests were used to check the antioxidant activities.