Formulation and Characterization of Pxolyherbal Buccal films incorporating Withania somnifera (L.) Dunal and Bacopa monnieri (L.) Pennell. for Cognitive support in Migraine Patients
Rajesh Kumar Sharma1 , Pawale Santosh Dnyanoba2 , Durga Prameela Gaddam3 , Pooja Jha4 , Sazedur Rahman Akanda5 , Dipanwita Chaudhuri Sil6 , Rajeev Garg7 , and Raj Kumari*8
1Department of Pharmacognosy, Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University, Delhi Road Moradabad-244001 (India) 2Department of RSBK, PMT’s Ayurved College Shevgaon District Ahilyanagar - 414502 (India) 3Department of Biological and Chemical Sciences, Mohan Babu University, Tirupati-517102 (India) 4Department of Food Technology, JAIN (Deemed-to-be- University), Bangalore: 562112 (India) 5School of Pharmaceutical Sciences, USTM, University of Science and Technology Meghalaya, Dist- Ribhoi - 793101 (India) 6Department of Botany, Holy Cross College, Agartala, Tripura - 799210 (India) 7Gurunanak Institute of Pharmacy, Dalewal- 144208, Dist. Hoshiarpur, (Postgraduate College affiliated with IKG Punjab Technical University), (India) 8 I.T.S College of Pharmacy, Murad Nagar, Ghaziabad - 201206 (India) *Corresponding author: Prof. (Dr.) Raj Kumari, Professor & Dean, I.T.S College of Pharmacy, Murad Nagar, Ghaziabad - 201206 (India)
ABSTRACT
Migraine is a debilitating neurological disorder often associated with cognitive dysfunction, including memory impairment, mental fatigue, and reduced concentration. Herbal nootropics such as Withania somnifera (Ashwagandha) and Bacopa monnieri (Brahmi) have shown promising potential in improving cognitive function and reducing stress. This study focuses on the formulation and characterization of polyherbalbuccal films containing standardized extracts of Withania somnifera and Bacopa monnieri intended for rapid mucosal absorption to enhance cognitive support in migraine patients