1S Leelavathy, 2A Jayathsenayai and 3*K Sheela

*1,3Department of Biochemistry, Sacred Heart College (Autonomous), (Affiliated to Thiruvalluvar University) Tirupathur - 635601 (India) 2Department of Physics, Marudhar Kesari Jain College for Women (Autonomous), (Affiliated to Thiruvalluvar University) Vaniyambadi – 635 751 (India) *3Corresponding author: Telephone +91-8778232818, Email:sheelabiochem2020@gmail.com

ABSTRACT

The herbal climber Momordica charantia Linn. (karela) is a member of the Cucurbitaceae family and is grown in tropical and subtropical climates. From ancient times to the present, Momordica charantia (Karela) has been used to treat a wide range of illnesses. It is inexpensive, harmless, and has been employed in many different processes. It is also widely utilized for its antioxidant, antibacterial, and anti-inflammatory properties. The strong oxidizing power of Momordica charantia L’s aqueous extract, which produces free radicals, encourages the inactivation of bacteria by slowing their growth. Extract from leaves in water using the Soxhlet technique. This study assessed the synthetic extract’s anti-inflammatory, antioxidant, and antibacterial properties. The bovine serum albumin/anti-denaturation assay was used to test for antiinflammatory activity; DPPH was used to test for antioxidants in vitro; and the Agar well diffusion method was used to test for antibacterial activity

Key words : Antibacterial activity; anti-inflammatory activity; DPPH assay; diclofenac.

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