Green synthesis of Boerhavia diffusa L. silver nanoparticles against multidrug-resistant bacteria
Sasi Lekha S.1* and S. Antony2
1*,2Department of Microbiology, Malankara Catholic College, Mariagiri, Kaliyakavilai - 629153 (India) Affiliated to Manonmaniam Sundaranar University, Tirunelveli, India. *Corresponding author : Sasi lekha. S, E-mail: reshmirp24@gmail.com
ABSTRACT
This study demonstrates the environmentally friendly production of silver nanoparticles (AgNPs) utilizing extract from Boerhavia diffusa, which is high in bioactive substances like caffeic acid and quercetin. These spherical, monodispersed AgNPs showed strong, concentration-dependent antibacterial action against Bacillus tropicus and Bacillus cereus, two Multi-Drug Resistant (MDR) soil microorganisms. The plant’s phytoconstituents, especially quercetin, successfully inhibit important bacterial enzymes like beta-lactamase, as further proven by molecular docking. All things considered, the study offers a viable framework for creating plant-mediated nanomaterials as potent substitutes for synthetic antibiotics in the fight against diseases that are resistant to them