Toxin-induced fissured palmoplantar dermatitis secondary to chronic occupational exposure to agricultural chemicals: A Case Report
1Navajyoth J, 2*Sariput N Bhosikar and 3Ajith Krishnan
1-3Department of Agada Tantra Evam Vidhi Vaidyaka, Parul Institute of Ayurved and Research, Vadodara - 391760 (India) drnavajyothjayachandran@gmail.com Postal Address of Corresponding author: Department of Agada Tantra Evam Vidhi Vaidyaka, Parul Institute of Ayurved and Research, Vadodara, Gujarat-Ishwarpura, Waghodia- 391760 (India) 2drbsariput@gmail.com
ABSTRACT
Occupational exposure to agricultural chemicals is a significant but often under-recognized cause of chronic dermatological conditions. This case report describes a 42-year-old male agricultural worker presenting with painful fissures, hyperkeratosis, scaling, itching, and blackish discoloration over both soles for 18 months, with marked seasonal exacerbation during harvesting periods. Clinical examination revealed symmetrical plantar hyperkeratosis with deep fissures and tenderness, impairing ambulation. Based on occupational history and morphology, the condition was diagnosed as toxin-induced fissured palmoplantar dermatitis secondary to chronic agrochemical exposure. From an integrative perspective, the presentation was correlated with Dooshivisha Janya Vipadika, indicating cumulative low-grade toxic insult manifesting as chronic plantar dermatosis. Management involved a detoxification-oriented approach followed by internal and external restorative therapies, along with dietary regulation and exposure control. Significant reduction in itching and pain was observed early, followed by progressive healing of fissures and improvement in skin texture within 14 days. Functional mobility improved substantially, though hyperpigmentation resolved more slowly. This case highlights the importance of detailed occupational history, recognition of cumulative toxic injury in chronic dermatoses, and the potential benefit of a comprehensive management strategy addressing both exposure and barrier restoration.