Study on the Toxic effects of Di-N-Butyl Phthalate on Male reproductive system: A review
Tina Pillare1 , Shikha Sethiya2 , Urmila Jiwantare3 , Yamini Makarwar4 and Varsha Dhurvey5*
1,2,3,4,5* Post Graduate Teaching Department of Zoology, RTM Nagpur University, Nagpur - 440033 (India) Email Address: 1 tinapillare1@gmail.com ; 2 shikhasethiya1@gmail.com ; 3 urmilajiwantare@gmail.com ; 4 makarwaryami@gmail.com ; 5* varshadhurvey@yahoo.com Corresponding Author, Email Address: 5* varshadhurvey@yahoo.com
ABSTRACT
Di-n-butyl phthalate (DBP) is a plasticizer in plastics, cosmetics, and many consumer products. People and the environment are regularly exposed to it. It is a significant chemical pollutant due to its widespread use and its ability to stay in the environment. This study aims to show the harmful effects of DBP on the male reproductive system. Several studies identify DBP as an endocrine disruptor. It can reduce hormone production, especially testosterone, and disrupt normal fertility processes. Exposure to DBP is also connected to poor sperm quality, testicular damage, oxidative stress, and developmental disorders. For assessing the hazards to eco-system and human health and for emphasizing the need of controlled use and more research we have to understand the toxic effects of DBP.