Pharmacodynamic Synergy of Tablet Yoga 2 Vati in the Management of Essential Hypertension
1Dipeeka Surawse, 2Naresh Kore and 3Prasanna Matad
1,2Department of Kayachikitsa, Parul Institute of Ayurved and Research Parul University, Ishwarpura - Limda, Vadodara - 391760 (India) 1Email Id – drdipeeka77@gmail.com 2Email ID- Naresh.kore86275@paruluniversity.ac.in 3Department of Rasashastra Evum Bhaishajya Kalpana, Parul Institute of Ayurved and Research, Parul University,Ishwarpura-Limda, Vadodara - 391760 (India) 3Email ID - Prasanna Mathad
ABSTRACT
Essential Hypertension (EH) is a global lifestyle disorder characterised by sustained elevation of systemic arterial blood pressure. In Ayurvedic physiology, EH is understood as a Tridoshaj Vyadhi with predominant involvement of Vyana Vayu (responsible for circulation) and Pitta Dushti (affecting blood/Rakta tissue and vascular tone). Conventional antihypertensive medications often necessitate multi-drug regimens and long-term dependency. Yoga 2 Vati, a multi-herbal formulation containing 14 classical Ayurvedic ingredients, offers a multitargeted therapeutic approach. To analyze the pharmacodynamic synergy, Rasa-Panchaka profile, and Dosha-Karma mechanisms of the 14 ingredients in Yoga 2 Vati in regulating arterial pressure, vascular resistance, and autonomic balance.